Key Points
- Stroke/central cause is the most critical diagnosis to exclude: look for the "5 Ds" of posterior circulation stroke: Dizziness, Diplopia, Dysarthria, Dysphagia, Dystaxia
- The HINTS exam (Head Impulse, Nystagmus, Test of Skew) is the key bedside tool for differentiating peripheral from central causes in acute vestibular syndrome, with reported 100% sensitivity and 96% specificity
- "Dizziness plus" any focal neurological symptom should raise concern for a central (vascular) aetiology
- Posterior circulation strokes are missed twice as often as anterior strokes due to non-specific symptoms like dizziness, nausea, and vomiting
- MRI can be false-negative in posterior circulation strokes within the first 48 hours
Red Flags Requiring Emergency Assessment
The following features alongside dizziness/vertigo suggest a potentially life-threatening cause (stroke, cardiac event, or serious neurological condition):
Neurological red flags (posterior circulation stroke/TIA):
- Focal neurological deficits: limb weakness or numbness, facial droop
- Dysarthria, diplopia, dysphagia, dysphonia
- Gait ataxia or severe truncal ataxia (inability to sit unsupported or walk)
- Downbeat nystagmus, pure torsional nystagmus, or bidirectional gaze-evoked nystagmus (central nystagmus patterns)
- New severe headache ("thunderclap" or unlike previous headaches)
- Depressed consciousness or confusion
Cardiac red flags:
- Chest pain, shortness of breath, or palpitations
- Syncope or pre-syncope
Other red flags:
- Acute unilateral hearing loss with vertigo (anterior inferior cerebellar artery territory)
- Dizziness following head trauma
- New-onset vertigo with fever and severe headache (consider CNS infection)
Key Clinical Considerations
The HINTS Exam
In patients with acute vestibular syndrome (continuous vertigo >24 hours with nystagmus), the bedside HINTS exam is critical:
- Head Impulse test: Normal (no corrective saccade) = worrisome for central cause
- Nystagmus: Direction-changing or vertical = central
- Test of Skew: Positive (vertical ocular misalignment) = central
HINTS plus incorporates acute hearing loss assessment, improving diagnostic accuracy.
High-Risk Populations
In older adults, dizziness is frequently multifactorial, and there is increased likelihood of serious underlying causes such as stroke or cardiovascular disease; a comprehensive assessment including medication review, sensory evaluation, and careful neurological/cardiac examination is essential.
Episodic Vertigo Red Flags
Recent-onset, brief recurrent episodes of dizziness lasting only minutes should raise concern for vertebrobasilar TIA, even if dizziness is the only symptom.
| Red Flag Category | Key Features | Concern |
|---|---|---|
| Focal neurology | Weakness, numbness, dysarthria, diplopia, dysphagia | Posterior circulation stroke |
| Central nystagmus | Downbeat, direction-changing, pure torsional | Central lesion |
| Gait failure | New inability to walk, severe truncal ataxia | Cerebellar stroke |
| Cardiac symptoms | Chest pain, dyspnoea, syncope | MI, arrhythmia |
| Acute hearing loss | Sudden unilateral loss with vertigo | AICA territory infarct |
| Post-traumatic | Dizziness after head injury | TBI/concussion |
| Brief recurrent episodes | New-onset, minutes duration | Vertebrobasilar TIA |
See sources cited
- [PDF] Posterior Circulation Stroke - American Heart Association
- 12 Key Principles for Diagnosing and Managing Vertigo and Dizziness
- Neurological Red Flags: A Missed Stroke after Intermittent Episodes of Dizziness and Headache - WebM&M: Case Studies - NCBI Bookshelf
- Vertigo in Clinical Practice: Evidence-Based Diagnosis and Treatment
- Acute vertigo: stroke or not? - PMC
- Frontiers | Hyperacute assessment of vertigo in suspected stroke
- Posterior Circulation Strokes - EMOttawa Blog
- Vertigo and Dizziness in the Emergency Department - PMC
- When to Go to the ER for Dizziness | Grand Strand Physicians
- Understanding Dizziness and Vertigo: When to Seek Urgent Care - MedHelp
- Vertigo Triggers in The Woodlands TX | Prince Health | Prince Health
Evidence Validator
Elliott Taylor

